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Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents
[Image: see text] Starting from known GLI1 inhibitors, a pharmacophore-based virtual screening approach was applied to databases of commercially available compounds with the aim of identifying new GLI1 modulators. As a result, three different chemical scaffolds emerged that were characterized by a s...
Enregistré dans:
| Publié dans: | ACS Med Chem Lett |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical
Society
2020
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7236221/ https://ncbi.nlm.nih.gov/pubmed/32435392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00639 |
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