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Structure-Based Pharmacophore Design and Virtual Screening for Novel Tubulin Inhibitors with Potential Anticancer Activity

Tubulin inhibitors have been considered as potential drugs for cancer therapy. However, their drug resistance and serious side-effects are the main reasons for clinical treatment failure. Therefore, there is still an urgent need to develop effective therapeutic drugs. Herein, a structure-based pharm...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zhou, Yunjiang, Di, Bin, Niu, Miao-Miao
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749218/
https://ncbi.nlm.nih.gov/pubmed/31480625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24173181
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