ロード中...

Identification of novel acetylcholinesterase inhibitors designed by pharmacophore-based virtual screening, molecular docking and bioassay

In this study, pharmacophore based 3D QSAR models for human acetylcholinesterase (AChE) inhibitors were generated, with good significance, statistical values (r(2)(training) = 0.73) and predictability (q(2)(training) = 0.67). It was further validated by three methods (Fischer’s test, decoy set and G...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Jang, Cheongyun, Yadav, Dharmendra K., Subedi, Lalita, Venkatesan, Ramu, Venkanna, Arramshetti, Afzal, Sualiha, Lee, Eunhee, Yoo, Jaewook, Ji, Eunhee, Kim, Sun Yeou, Kim, Mi-hyun
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175823/
https://ncbi.nlm.nih.gov/pubmed/30297729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33354-6
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!