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Virtual screening and pharmacophore studies for ftase inhibitors using Indian plant anticancer compounds database

Farnesyl transferase (FTase) is an enzyme responsible for post-translational modification in proteins having a carboxy-terminal CaaX motif in human. It catalyzes the attachment of a lipid group in proteins of RAS superfamily, which is essential in signal transduction. FTase has been recognized as an...

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מידע ביבליוגרפי
Main Authors: Khan, Abdul Hafeez, Prakash, Alok, Kumar, Dinesh, Rawat, Anil Kumar, Srivastava, Rajeev, Srivastava, Shipra
פורמט: Artigo
שפה:Inglês
יצא לאור: Biomedical Informatics 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039991/
https://ncbi.nlm.nih.gov/pubmed/21346865
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