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Aurora kinase inhibitor tozasertib suppresses mast cell activation in vitro and in vivo
BACKGROUND AND PURPOSE: Mast cells are important in allergic reactions. Here, we assessed the anti‐allergic effects of the anti‐cancer drug tozasertib specifically regarding regulatory effects on mast cell activation. EXPERIMENTAL APPROACH: Tozasertib effects on mast cell degranulation were determin...
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| Udgivet i: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7236079/ https://ncbi.nlm.nih.gov/pubmed/32017040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15012 |
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