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Aurora kinase inhibitor tozasertib suppresses mast cell activation in vitro and in vivo

BACKGROUND AND PURPOSE: Mast cells are important in allergic reactions. Here, we assessed the anti‐allergic effects of the anti‐cancer drug tozasertib specifically regarding regulatory effects on mast cell activation. EXPERIMENTAL APPROACH: Tozasertib effects on mast cell degranulation were determin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Pharmacol
Egile Nagusiak: Zhang, Li‐Na, Ji, Kunmei, Sun, Yue‐Tong, Hou, Yi‐Bo, Chen, Jia‐Jie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236079/
https://ncbi.nlm.nih.gov/pubmed/32017040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15012
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