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CDK4/6 inhibitor palbociclib suppresses IgE-mediated mast cell activation
BACKGROUND: Mast cell activation causes degranulation and release of cytokines, thereby promoting inflammation. The aim of this study was to investigate the inhibitory effect of CDK4/6 inhibition on mast cell activation in vitro and in vivo. METHODS: RBL-2H3 rat basophilic leukemia cells (BLCs) and...
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| Vydáno v: | J Transl Med |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6702723/ https://ncbi.nlm.nih.gov/pubmed/31429774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-2026-9 |
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