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ABCG2 impairs the activity of the aurora kinase inhibitor tozasertib but not of alisertib
BACKGROUND: Recently, we have shown that the ATP-binding cassette (ABC) transporter ABCB1 interferes with the anti-cancer activity of the pan-aurora kinase inhibitor tozasertib (VX680, MK-0457) but not of the aurora kinase A and B inhibitor alisertib (MLN8237). Preliminary data had suggested tozaser...
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| Pubblicato in: | BMC Res Notes |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4587578/ https://ncbi.nlm.nih.gov/pubmed/26415506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-015-1405-4 |
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