Association between acquired resistance to PLX4032 (vemurafenib) and ATP-binding cassette transporter expression

BACKGROUND: Various kinase inhibitors are known to be ATP-binding cassette (ABC) transporter substrates and resistance acquisition to kinase inhibitors has been associated to increased ABC transporter expression. Here, we investigated the role of the ABC transporters ABCB1, ABCC1, and ABCG2 during m...

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מידע ביבליוגרפי
Main Authors: Michaelis, Martin, Rothweiler, Florian, Nerreter, Thomas, van Rikxoort, Marijke, Zehner, Richard, Dirks, Wilhelm G, Wiese, Michael, Cinatl, Jindrich
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2014
נושאים:
Short Report
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197243/
https://ncbi.nlm.nih.gov/pubmed/25300205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-710
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