Association between acquired resistance to PLX4032 (vemurafenib) and ATP-binding cassette transporter expression

BACKGROUND: Various kinase inhibitors are known to be ATP-binding cassette (ABC) transporter substrates and resistance acquisition to kinase inhibitors has been associated to increased ABC transporter expression. Here, we investigated the role of the ABC transporters ABCB1, ABCC1, and ABCG2 during m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Michaelis, Martin, Rothweiler, Florian, Nerreter, Thomas, van Rikxoort, Marijke, Zehner, Richard, Dirks, Wilhelm G, Wiese, Michael, Cinatl, Jindrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Short Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197243/
https://ncbi.nlm.nih.gov/pubmed/25300205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-710
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