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Aurora Kinases as Targets in Drug-Resistant Neuroblastoma Cells

Aurora kinase inhibitors displayed activity in pre-clinical neuroblastoma models. Here, we studied the effects of the pan-aurora kinase inhibitor tozasertib (VX680, MK-0457) and the aurora kinase inhibitor alisertib (MLN8237) that shows some specificity for aurora kinase A over aurora kinase B in a...

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Detalhes bibliográficos
Main Authors: Michaelis, Martin, Selt, Florian, Rothweiler, Florian, Löschmann, Nadine, Nüsse, Benedikt, Dirks, Wilhelm G., Zehner, Richard, Cinatl, Jindrich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182628/
https://ncbi.nlm.nih.gov/pubmed/25268132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108758
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