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Conformationally restricted monosaccharide-cored glycoside amphiphiles: the effect of detergent head group variation on membrane protein stability

Detergents are widely used to isolate membrane proteins from lipid bilayers, but many proteins solubilized in conventional detergents are structurally unstable. Thus, there is major interest in the development of novel amphiphiles to facilitate membrane protein research. In the present study, we hav...

詳細記述

保存先:
書誌詳細
出版年:ACS Chem Biol
主要な著者: Sadaf, Aiman, Ramos, Manuel, Mortensen, Jonas S., Du, Yang, Bae, Hyoung Eun, Munk, Chastine F., Hariharan, Parameswaran, Byrne, Bernadette, Kobilka, Brian K., Loland, Claus J., Guan, Lan, Seok Chae, Pil
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233146/
https://ncbi.nlm.nih.gov/pubmed/31305987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00166
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