Conformationally restricted monosaccharide-cored glycoside amphiphiles: the effect of detergent head group variation on membrane protein stability

Detergents are widely used to isolate membrane proteins from lipid bilayers, but many proteins solubilized in conventional detergents are structurally unstable. Thus, there is major interest in the development of novel amphiphiles to facilitate membrane protein research. In the present study, we hav...

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Bibliografske podrobnosti
izdano v:ACS Chem Biol
Main Authors: Sadaf, Aiman, Ramos, Manuel, Mortensen, Jonas S., Du, Yang, Bae, Hyoung Eun, Munk, Chastine F., Hariharan, Parameswaran, Byrne, Bernadette, Kobilka, Brian K., Loland, Claus J., Guan, Lan, Seok Chae, Pil
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233146/
https://ncbi.nlm.nih.gov/pubmed/31305987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00166
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