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Rationally engineered tandem facial amphiphiles for improved membrane protein stabilization efficacy
A new family of tandem facial glucoside/maltosides (TFG/TFMs) for membrane protein manipulation is reported. The best detergent varied depending on the hydrophobic thickness of the target protein, but ether-based TFMs (TFM-C0E, TFM-C3E or TFM-C5E) were notable for their ability to confer enhanced me...
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| Udgivet i: | Chembiochem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7233144/ https://ncbi.nlm.nih.gov/pubmed/30070754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800388 |
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