Tandem Facial Amphiphiles for Membrane Protein Stabilization

We describe a new type of synthetic amphiphile that is intended to support biochemical characterization of intrinsic membrane proteins. Members of this new family displayed favorable behavior with four of five membrane proteins tested, and these amphiphiles formed relatively small micelles.

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Autors principals: Chae, Pil Seok, Gotfryd, Kamil, Pacyna, Jennifer, Miercke, Larry J. W., Rasmussen, Søren G. F., Robbins, Rebecca A., Rana, Rohini R., Loland, Claus J., Kobilka, Brian, Stroud, Robert, Byrne, Bernadette, Gether, Ulrik, Gellman, Samuel H.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050673/
https://ncbi.nlm.nih.gov/pubmed/21049926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1072959
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