Tandem Facial Amphiphiles for Membrane Protein Stabilization

We describe a new type of synthetic amphiphile that is intended to support biochemical characterization of intrinsic membrane proteins. Members of this new family displayed favorable behavior with four of five membrane proteins tested, and these amphiphiles formed relatively small micelles.

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Bibliographic Details
Main Authors: Chae, Pil Seok, Gotfryd, Kamil, Pacyna, Jennifer, Miercke, Larry J. W., Rasmussen, Søren G. F., Robbins, Rebecca A., Rana, Rohini R., Loland, Claus J., Kobilka, Brian, Stroud, Robert, Byrne, Bernadette, Gether, Ulrik, Gellman, Samuel H.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050673/
https://ncbi.nlm.nih.gov/pubmed/21049926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1072959
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