Tandem Facial Amphiphiles for Membrane Protein Stabilization

We describe a new type of synthetic amphiphile that is intended to support biochemical characterization of intrinsic membrane proteins. Members of this new family displayed favorable behavior with four of five membrane proteins tested, and these amphiphiles formed relatively small micelles.

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Detalhes bibliográficos
Main Authors: Chae, Pil Seok, Gotfryd, Kamil, Pacyna, Jennifer, Miercke, Larry J. W., Rasmussen, Søren G. F., Robbins, Rebecca A., Rana, Rohini R., Loland, Claus J., Kobilka, Brian, Stroud, Robert, Byrne, Bernadette, Gether, Ulrik, Gellman, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050673/
https://ncbi.nlm.nih.gov/pubmed/21049926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1072959
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