Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction

Disabling hearing loss impacts ∼466 million individuals worldwide with 34 million children affected. Gene and pharmacotherapeutic strategies to rescue auditory function in mouse models of human deafness are most effective when administered before hearing onset, after which therapeutic efficacy is si...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Wang, Lingyan, Kempton, J Beth, Jiang, Han, Jodelka, Francine M, Brigande, Alev M, Dumont, Rachel A, Rigo, Frank, Lentz, Jennifer J, Hastings, Michelle L, Brigande, John V
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
RNA and RNA-protein complexes
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229850/
https://ncbi.nlm.nih.gov/pubmed/32249312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa194
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