Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction

Disabling hearing loss impacts ∼466 million individuals worldwide with 34 million children affected. Gene and pharmacotherapeutic strategies to rescue auditory function in mouse models of human deafness are most effective when administered before hearing onset, after which therapeutic efficacy is si...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Wang, Lingyan, Kempton, J Beth, Jiang, Han, Jodelka, Francine M, Brigande, Alev M, Dumont, Rachel A, Rigo, Frank, Lentz, Jennifer J, Hastings, Michelle L, Brigande, John V
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
RNA and RNA-protein complexes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229850/
https://ncbi.nlm.nih.gov/pubmed/32249312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa194
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