Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction

Disabling hearing loss impacts ∼466 million individuals worldwide with 34 million children affected. Gene and pharmacotherapeutic strategies to rescue auditory function in mouse models of human deafness are most effective when administered before hearing onset, after which therapeutic efficacy is si...

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Bibliographic Details
Published in:	Nucleic Acids Res
Main Authors:	Wang, Lingyan, Kempton, J Beth, Jiang, Han, Jodelka, Francine M, Brigande, Alev M, Dumont, Rachel A, Rigo, Frank, Lentz, Jennifer J, Hastings, Michelle L, Brigande, John V
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2020
Subjects:	RNA and RNA-protein complexes
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7229850/ https://ncbi.nlm.nih.gov/pubmed/32249312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa194
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Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction

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