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Rescue of Outer Hair Cells with Antisense Oligonucleotides in Usher Mice Is Dependent on Age of Treatment

The absence of functional outer hair cells is a component of several forms of hereditary hearing impairment, including Usher syndrome, the most common cause of concurrent hearing and vision loss. Antisense oligonucleotide (ASO) treatment of mice with the human Usher mutation, Ush1c c.216G>A, corr...

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Publicado en:J Assoc Res Otolaryngol
Main Authors: Ponnath, Abhilash, Depreux, Frederic F., Jodelka, Francine M., Rigo, Frank, Farris, Hamilton E., Hastings, Michelle L., Lentz, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783922/
https://ncbi.nlm.nih.gov/pubmed/29027038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-017-0640-x
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