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Quantitative analysis of transcription factor binding and expression using calling cards reporter arrays
We report a tool, Calling Cards Reporter Arrays (CCRA), that measures transcription factor (TF) binding and the consequences on gene expression for hundreds of synthetic promoters in yeast. Using Cbf1p and MAX, we demonstrate that the CCRA method is able to detect small changes in binding free energ...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7229839/ https://ncbi.nlm.nih.gov/pubmed/32133534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa141 |
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