Calling Cards enable multiplexed identification of the genomic targets of DNA-binding proteins

Transcription factors direct gene expression, so there is much interest in mapping their genome-wide binding locations. Current methods do not allow for the multiplexed analysis of TF binding, and this limits their throughput. We describe a novel method for determining the genomic target genes of mu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Haoyi, Mayhew, David, Chen, Xuhua, Johnston, Mark, Mitra, Robi David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2011
Pynciau:
Method
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083092/
https://ncbi.nlm.nih.gov/pubmed/21471402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.114850.110
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