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Quantitative high-throughput analysis of transcription factor binding specificities
We present a general high-throughput approach to accurately quantify DNA–protein interactions, which can facilitate the identification of functional genetic polymorphisms. The method tested here on two structurally distinct transcription factors (TFs), NF-κB and OCT-1, comprises three steps: (i) opt...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390317/ https://ncbi.nlm.nih.gov/pubmed/14990752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh042 |
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