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Nono deficiency compromises TET1 chromatin association and impedes neuronal differentiation of mouse embryonic stem cells

NONO is a DNA/RNA-binding protein, which plays a critical regulatory role during cell stage transitions of mouse embryonic stem cells (mESCs). However, its function in neuronal lineage commitment and the molecular mechanisms of its action in such processes are largely unknown. Here we report that NO...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Li, Wenjing, Karwacki-Neisius, Violetta, Ma, Chun, Tan, Li, Shi, Yang, Wu, Feizhen, Shi, Yujiang Geno
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229820/
https://ncbi.nlm.nih.gov/pubmed/32286661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa213
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