Nono, a bivalent domain factor, regulates Erk signaling and mouse embryonic stem cell pluripotency

Nono is a component of the para-speckle, which stores and processes RNA. Mouse embryonic stem cells (mESCs) lack para-speckles, leaving the function of Nono in mESCs unclear. Here we find that Nono functions as a chromatin regulator cooperating with Erk to regulate mESC pluripotency. We report that...

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Publicado no:Cell Rep
Main Authors: Ma, Chun, Karwacki-Neisius, Violetta, Tang, Haoran, Li, Wenjing, Shi, Zhennan, Hu, Haolin, Xu, Wenqi, Wang, Zhentian, Kong, Lingchun, Lv, Ruitu, Fan, Zheng, Zhou, Wenhao, Yang, Pengyuan, Wu, Feizhen, Diao, Jianbo, Tan, Li, Shi, Yujiang Geno, Lan, Fei, Shi, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086807/
https://ncbi.nlm.nih.gov/pubmed/27760330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.078
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