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Nono, a bivalent domain factor, regulates Erk signaling and mouse embryonic stem cell pluripotency
Nono is a component of the para-speckle, which stores and processes RNA. Mouse embryonic stem cells (mESCs) lack para-speckles, leaving the function of Nono in mESCs unclear. Here we find that Nono functions as a chromatin regulator cooperating with Erk to regulate mESC pluripotency. We report that...
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| Опубликовано в: : | Cell Rep |
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| Главные авторы: | , , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5086807/ https://ncbi.nlm.nih.gov/pubmed/27760330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.078 |
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