A primary role of TET proteins in establishment and maintenance of De Novo bivalency at CpG islands

Ten Eleven Translocation (TET) protein-catalyzed 5mC oxidation not only creates novel DNA modifications, such as 5hmC, but also initiates active or passive DNA demethylation. TETs’ role in the crosstalk with specific histone modifications, however, is largely elusive. Here, we show that TET2-mediate...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kong, Lingchun, Tan, Li, Lv, Ruitu, Shi, Zhennan, Xiong, Lijun, Wu, Feizhen, Rabidou, Kimberlie, Smith, Michael, He, Celestine, Zhang, Lei, Qian, Yanyan, Ma, Duan, Lan, Fei, Shi, Yang, Shi, Yujiang Geno
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062965/
https://ncbi.nlm.nih.gov/pubmed/27288448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw529
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