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Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved

DNA methylation is a repressive epigenetic modification that covers vertebrate genomes. Regions known as CpG islands (CGIs), which are refractory to DNA methylation, are often associated with gene promoters and play central roles in gene regulation. Yet how CGIs in their normal genomic context evade...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Long, Hannah K., King, Hamish W., Patient, Roger K., Odom, Duncan T., Klose, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001583/
https://ncbi.nlm.nih.gov/pubmed/27084945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw258
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