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Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved

DNA methylation is a repressive epigenetic modification that covers vertebrate genomes. Regions known as CpG islands (CGIs), which are refractory to DNA methylation, are often associated with gene promoters and play central roles in gene regulation. Yet how CGIs in their normal genomic context evade...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Long, Hannah K., King, Hamish W., Patient, Roger K., Odom, Duncan T., Klose, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001583/
https://ncbi.nlm.nih.gov/pubmed/27084945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw258
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