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Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved

DNA methylation is a repressive epigenetic modification that covers vertebrate genomes. Regions known as CpG islands (CGIs), which are refractory to DNA methylation, are often associated with gene promoters and play central roles in gene regulation. Yet how CGIs in their normal genomic context evade...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Long, Hannah K., King, Hamish W., Patient, Roger K., Odom, Duncan T., Klose, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001583/
https://ncbi.nlm.nih.gov/pubmed/27084945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw258
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