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Nono deficiency compromises TET1 chromatin association and impedes neuronal differentiation of mouse embryonic stem cells

NONO is a DNA/RNA-binding protein, which plays a critical regulatory role during cell stage transitions of mouse embryonic stem cells (mESCs). However, its function in neuronal lineage commitment and the molecular mechanisms of its action in such processes are largely unknown. Here we report that NO...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Li, Wenjing, Karwacki-Neisius, Violetta, Ma, Chun, Tan, Li, Shi, Yang, Wu, Feizhen, Shi, Yujiang Geno
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229820/
https://ncbi.nlm.nih.gov/pubmed/32286661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa213
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