Quantitative Proteomics Identifies TCF1 as a Negative Regulator of Foxp3 Expression in Conventional T Cells

Regulatory T cells are important regulators of the immune system and have versatile functions for the homeostasis and repair of tissues. They express the forkhead box transcription factor Foxp3 as a lineage-defining protein. Negative regulators of Foxp3 expression are not well understood. Here, we g...

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Gepubliceerd in:iScience
Hoofdauteurs: Delacher, Michael, Barra, Melanie M., Herzig, Yonatan, Eichelbaum, Katrin, Rafiee, Mahmoud-Reza, Richards, David M., Träger, Ulrike, Hofer, Ann-Cathrin, Kazakov, Alexander, Braband, Kathrin L., Gonzalez, Marina, Wöhrl, Lukas, Schambeck, Kathrin, Imbusch, Charles D., Abramson, Jakub, Krijgsveld, Jeroen, Feuerer, Markus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229326/
https://ncbi.nlm.nih.gov/pubmed/32422593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101127
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