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Premature Expression of Foxp3 in Double-Negative Thymocytes
Peripheral immune regulation depends on the generation of thymic-derived regulatory T (tT(reg)) cells to maintain self-tolerance and to counterbalance overshooting immune responses. The expression of the T(reg) lineage defining transcription factor Foxp3 in developing tT(reg) cells depends on TCR si...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433242/ https://ncbi.nlm.nih.gov/pubmed/25978037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127038 |
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