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The route to transcription initiation determines the mode of transcriptional bursting in E. coli

Transcription is fundamentally noisy, leading to significant heterogeneity across bacterial populations. Noise is often attributed to burstiness, but the underlying mechanisms and their dependence on the mode of promotor regulation remain unclear. Here, we measure E. coli single cell mRNA levels for...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Engl, Christoph, Jovanovic, Goran, Brackston, Rowan D., Kotta-Loizou, Ioly, Buck, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229158/
https://ncbi.nlm.nih.gov/pubmed/32415118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16367-6
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