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Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation

Gene transcription is carried out by multi-subunit RNA polymerases (RNAPs). Transcription initiation is a dynamic multi-step process that involves the opening of the double-stranded DNA to form a transcription bubble and delivery of the template strand deep into the RNAP for RNA synthesis. Applying...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Glyde, Robert, Ye, Fuzhou, Jovanovic, Milija, Kotta-Loizou, Ioly, Buck, Martin, Zhang, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028918/
https://ncbi.nlm.nih.gov/pubmed/29932903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.05.021
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