Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7

Bacteriophage T7 infects Escherichia coli and evades the host restriction/modification system. The Ocr protein of T7 was shown to exist as a dimer mimicking DNA and to bind to host restriction enzymes, thus preventing the degradation of the viral genome by the host. Here we report that Ocr can also...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Ye, Fuzhou, Kotta-Loizou, Ioly, Jovanovic, Milija, Liu, Xiaojiao, Dryden, David TF, Buck, Martin, Zhang, Xiaodong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2020
Gaiak:
Structural Biology and Molecular Biophysics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064336/
https://ncbi.nlm.nih.gov/pubmed/32039758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52125
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