Dissection of the DNA Mimicry of the Bacteriophage T7 Ocr Protein using Chemical Modification

The homodimeric Ocr (overcome classical restriction) protein of bacteriophage T7 is a molecular mimic of double-stranded DNA and a highly effective competitive inhibitor of the bacterial type I restriction/modification system. The surface of Ocr is replete with acidic residues that mimic the phospha...

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Main Authors: Stephanou, Augoustinos S., Roberts, Gareth A., Cooper, Laurie P., Clarke, David J., Thomson, Andrew R., MacKay, C. Logan, Nutley, Margaret, Cooper, Alan, Dryden, David T.F.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806950/
https://ncbi.nlm.nih.gov/pubmed/19523474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.06.020
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