Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation

Gene transcription is carried out by RNA polymerases (RNAPs). For transcription to occur, the closed promoter complex (RPc), where DNA is double stranded, must isomerize into an open promoter complex (RPo), where the DNA is melted out into a transcription bubble and the single-stranded template DNA...

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Glyde, Robert, Ye, Fuzhou, Darbari, Vidya Chandran, Zhang, Nan, Buck, Martin, Zhang, Xiaodong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505868/
https://ncbi.nlm.nih.gov/pubmed/28579332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.05.010
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