Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation

Gene transcription is carried out by RNA polymerases (RNAPs). For transcription to occur, the closed promoter complex (RPc), where DNA is double stranded, must isomerize into an open promoter complex (RPo), where the DNA is melted out into a transcription bubble and the single-stranded template DNA...

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Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Glyde, Robert, Ye, Fuzhou, Darbari, Vidya Chandran, Zhang, Nan, Buck, Martin, Zhang, Xiaodong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505868/
https://ncbi.nlm.nih.gov/pubmed/28579332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.05.010
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