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The route to transcription initiation determines the mode of transcriptional bursting in E. coli

Transcription is fundamentally noisy, leading to significant heterogeneity across bacterial populations. Noise is often attributed to burstiness, but the underlying mechanisms and their dependence on the mode of promotor regulation remain unclear. Here, we measure E. coli single cell mRNA levels for...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Engl, Christoph, Jovanovic, Goran, Brackston, Rowan D., Kotta-Loizou, Ioly, Buck, Martin
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229158/
https://ncbi.nlm.nih.gov/pubmed/32415118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16367-6
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