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Phosphorylation Modulates the Coregulatory Protein Exchange of the Nuclear Receptor Pregnane X Receptor
The pregnane X receptor (PXR), or nuclear receptor (NR) 1I2, is a ligand-activated NR superfamily member that is enriched in liver and intestine in mammals. Activation of PXR regulates the expression of genes encoding key proteins involved in drug metabolism, drug efflux, and drug transport. Recent...
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| Vydáno v: | J Pharmacol Exp Ther |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7228503/ https://ncbi.nlm.nih.gov/pubmed/32205367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.264762 |
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