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SUMOylation and Ubiquitylation Circuitry Controls Pregnane X Receptor Biology in Hepatocytes

Several nuclear receptor (NR) superfamily members are known to be the molecular target of either the small ubiquitin-related modifier (SUMO) or ubiquitin-signaling pathways. However, little is currently known regarding how these two post-translational modifications interact to control NR biology. We...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Cui, Wenqi, Sun, Mengxi, Galeva, Nadezhda, Williams, Todd D., Azuma, Yoshiaki, Staudinger, Jeff L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538856/
https://ncbi.nlm.nih.gov/pubmed/26063058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.065201
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