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SUMOylation and Ubiquitylation Circuitry Controls Pregnane X Receptor Biology in Hepatocytes

Several nuclear receptor (NR) superfamily members are known to be the molecular target of either the small ubiquitin-related modifier (SUMO) or ubiquitin-signaling pathways. However, little is currently known regarding how these two post-translational modifications interact to control NR biology. We...

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Vydáno v:Drug Metab Dispos
Hlavní autoři: Cui, Wenqi, Sun, Mengxi, Galeva, Nadezhda, Williams, Todd D., Azuma, Yoshiaki, Staudinger, Jeff L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538856/
https://ncbi.nlm.nih.gov/pubmed/26063058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.065201
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