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Pregnane X Receptor Modulates the Inflammatory Response in Primary Cultures of Hepatocytes

Bacterial sepsis is characterized by a rapid increase in the expression of inflammatory mediators to initiate the acute phase response in liver. Inflammatory mediator release is counterbalanced by the coordinated expression of anti-inflammatory molecules such as interleukin 1 receptor antagonist (IL...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Sun, Mengxi, Cui, Wenqi, Woody, Sarah K., Staudinger, Jeff L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352581/
https://ncbi.nlm.nih.gov/pubmed/25527709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.062307
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