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A Systematic Analysis of Predicted Phosphorylation Sites within the Human Pregnane X Receptor Protein
The pregnane X receptor (PXR, NR1I2) regulates the expression of genes that encode drug-metabolizing enzymes and drug transporter proteins in liver and intestine. Understanding the molecular mechanisms that modulate PXR activity is therefore critical for the development of effective therapeutic stra...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Pharmacology and Experimental Therapeutics
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766221/ https://ncbi.nlm.nih.gov/pubmed/19617467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.157180 |
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