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Cyclic AMP-dependent Protein Kinase Signaling Modulates Pregnane x Receptor Activity in a Species-specific Manner

Pregnane x receptor is a ligand-activated transcription factor that regulates drug-inducible expression of several key cytochrome P450 enzymes and drug transporter proteins in liver and intestine in a species-specific manner. Activation of this receptor modulates several key biochemical pathways, in...

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Detalhes bibliográficos
Main Authors: Lichti-Kaiser, Kristin, Xu, Chenshu, Staudinger, Jeff L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652295/
https://ncbi.nlm.nih.gov/pubmed/19141612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807426200
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