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The Mycoestrogen Zearalenone Induces CYP3A through Activation of the Pregnane X Receptor
Zearalenone is a mycoestrogen that is produced in the fungi Fusarium graminearum, Fusarium culmorum, Fusarium equiseti, and Fusarium crookwellense. These fungi commonly exist in agricultural products. Human pregnane X receptor (hPXR) is a ligand-activated transcription factor that regulates the expr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981864/ https://ncbi.nlm.nih.gov/pubmed/16547076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfj163 |
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