Surface Composition and Formulation Heterogeneity of Protein Solids Produced by Spray Drying

PURPOSE: The aim of this study is to determine the effects of saccharide-containing excipients on the surface composition of spray-dried protein formulations and their matrix heterogeneity. METHODS: Spray-dried formulations of myoglobin or bovine serum albumin (BSA) were prepared without excipient o...

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Gepubliceerd in:Pharm Res
Hoofdauteurs: Wilson, Nathan E., Mutukuri, Tarun Tejasvi, Zemlyanov, Dmitry Y., Taylor, Lynne S., Topp, Elizabeth M., Zhou, Qi (Tony)
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227480/
https://ncbi.nlm.nih.gov/pubmed/31873808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-019-2738-9
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