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Pharmaceutical protein solids: drying technology, solid-state characterization and stability

Despite the boom in biologics over the past decade, the intrinsic instability of these large molecules poses significant challenges to formulation development. Almost half of all pharmaceutical protein products are formulated in the solid form to preserve protein native structure and extend product...

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Bibliografiske detaljer
Udgivet i:Adv Drug Deliv Rev
Main Authors: Chen, Yuan, Mutukuri, Tarun Tejasvi, Wilson, Nathan E., Zhou, Qi (Tony)
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107147/
https://ncbi.nlm.nih.gov/pubmed/33705880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2021.02.016
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