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Pharmaceutical protein solids: drying technology, solid-state characterization and stability

Despite the boom in biologics over the past decade, the intrinsic instability of these large molecules poses significant challenges to formulation development. Almost half of all pharmaceutical protein products are formulated in the solid form to preserve protein native structure and extend product...

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Detalhes bibliográficos
Publicado no:Adv Drug Deliv Rev
Main Authors: Chen, Yuan, Mutukuri, Tarun Tejasvi, Wilson, Nathan E., Zhou, Qi (Tony)
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107147/
https://ncbi.nlm.nih.gov/pubmed/33705880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2021.02.016
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