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Effects of Drying Method and Excipient on the Structure and Physical Stability of Protein Solids: Freeze Drying vs. Spray Freeze Drying

This study aims to determine the impacts of drying method and excipient on changes in protein structure and physical stability of model protein solids. Protein solids containing one of two model proteins (lysozyme or myoglobin) were produced with or without excipients (sucrose or mannitol) using fre...

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Detalhes bibliográficos
Publicado no:Int J Pharm
Main Authors: Mutukuri, Tarun Tejasvi, Wilson, Nathan E., Taylor, Lynne S., Topp, Elizabeth M., Zhou, Qi Tony
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856218/
https://ncbi.nlm.nih.gov/pubmed/33333176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2020.120169
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