Abnormal Cullin1 neddylation-mediated p21 accumulation participates in the pathogenesis of recurrent spontaneous abortion by regulating trophoblast cell proliferation and differentiation

The study explores the role of neddylation in early trophoblast development and its alteration during the pathogenesis of recurrent spontaneous abortion (RSA). Immunofluorescence and western blot were conducted to evaluate the expression pattern of NEDD8 protein in the first-trimester placentas of h...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Hum Reprod
Auteurs principaux: Sun, Xiaohe, Tong, Xiaomei, Hao, Yanqing, Li, Chao, Zhang, Yinli, Pan, Yibin, Dai, Yongdong, Liu, Liu, Zhang, Tai, Zhang, Songying
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227182/
https://ncbi.nlm.nih.gov/pubmed/32186736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gaaa021
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