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Anticancer drug discovery by targeting cullin neddylation
Protein neddylation is a post-translational modification which transfers the ubiquitin-like protein NEDD8 to a lysine residue of the target substrate through a three-step enzymatic cascade. The best-known substrates of neddylation are cullin family proteins, which are the core component of Cullin–RI...
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| Publicado no: | Acta Pharm Sin B |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7276695/ https://ncbi.nlm.nih.gov/pubmed/32528826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.09.005 |
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