Laddar...
Targeting Protein Neddylation to Inactivate Cullin-RING Ligases by Gossypol: A Lucky Hit or a New Start?
Cullin-RING E3 ligases (CRLs) are the largest family of E3 ubiquitin ligases, responsible for about 20% of the protein degradation by the ubiquitin-proteasome system (UPS). Given their vital roles in multiple cellular processes, and over-activation in many human cancers, CRLs are validated as promis...
Sparad:
| I publikationen: | Drug Des Devel Ther |
|---|---|
| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Dove
2021
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7797302/ https://ncbi.nlm.nih.gov/pubmed/33442232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S286373 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|