Targeted PARP Inhibition Combined with FGFR1 Blockade is Synthetically Lethal to Malignant Cells in Patients with Pancreatic Cancer

The role and therapeutic promise of poly-ADP ribose polymerase (PARP) inhibitors in anticancer chemotherapy are increasingly being explored, particularly in adjuvant or maintenance therapy, considering their low efficacy as monotherapy agents and their potentiating effects on concurrently administer...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Lai, Shiue-Wei, Bamodu, Oluwaseun Adebayo, Chen, Jia-Hong, Wu, Alexander TH, Lee, Wei-Hwa, Chao, Tsu-Yi, Yeh, Chi-Tai
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226837/
https://ncbi.nlm.nih.gov/pubmed/32276472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040911
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