p53 and FBXW7: Sometimes Two Guardians Are Worse than One

Too much of a good thing can become a bad thing. An example is FBXW7, a well-known tumor suppressor that may also contribute to tumorigenesis. Here, we reflect on the results of three laboratories describing the role of FBXW7 in the degradation of p53 and the possible implications of this finding in...

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Gardado en:
Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: Galindo-Moreno, María, Giráldez, Servando, Limón-Mortés, M. Cristina, Belmonte-Fernández, Alejandro, Sáez, Carmen, Japón, Miguel Á., Tortolero, Maria, Romero, Francisco
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
Assuntos:
Perspective
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225930/
https://ncbi.nlm.nih.gov/pubmed/32316282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040985
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